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The problem turned out to be egr upgrade that was never done on car. This includes a upgrade to the egr with upgraded harness and bigger pipe....
Here are the failure codes listed P0302--Cylinder 2 misfire P0301--Cylinder 1 misfire P0304--Cylinder 4 Misfire P0300--Random/Mulitiple cylinder...
First time poster here but I have owned my 2010 prius now for 10 yrs..Never had anything go wrong..Car has 280K miles on it..I love the car...