2011 Prius bogging or am engine shakes when I accelerate

i am having problems with my Prius. I have a 2011 prius with 145000 miles. I also have issues with the engine shakes initial idle and goes away with check engine light saying 2 & 4 misfire. Also I had a couple off issues where I was at a dead stop and when I accelerate the engine would feel like it Boggs and shakes from 0-20 mph then go away after. From 20-80 mph it's perfectly fine. Has anyone had the same issues? I am new here and any feedback would be great! Thank you!

 

I am at a complete loss here and have no idea what it could be. I have changed my spark plugs at 90k, transaxle flush at 90k, change synthetic oil every 7500 miles. Although I have very high mileage. Roughly 145,000 miles

Thank you!

I've changed plugs but not the coil packs. Ok... Seems like I need to change a bunch of stuff. Thank you for the feedback

EDIT: I just found it my head gasket is leaking coolant into my head, does anyone know how much this will cost to fix it