SARS-CoV-2 Coronavirus (COVID-19)

I am not sure where you are going with this? But it probably belong to the another forum, so I am not going to respond.

 

if anyone wanted to reduce the population, they wouldn't be promoting any types of vaccines or cures. the virus is doing the heavy work

 

. . . the sun is another source for vitamin D, & during the 4 weeks that they called a handful of us back to work, most of it has been outside - not that vitamin D or an unbalanced diet has ever been a concern. It's likely that not getting stuck indoors has a big part to do with avoiding things like flu, Wuhan or otherwise.
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Of the approximately 1 billion annual common colds in the U.S., four coronaviruses cause about 200 billion of them. But there are only about 4 million births per year plus 1 million new immigrants. Very crudely, that means each U.S. resident averages 40 common colds per lifetime from just 4 coronaviruses. Or crudely, 10 colds per lifetime from each coronavirus.

That suggests that immunity to each prior known coronavirus, doesn't last long. Will Covid-19 be any different?

 

A common cold is a discomfort whose symptoms can be handled with over-the-counter meds, chicken soup, and a couple of days off. In contrast, COVID-19 has a 1-in-5 chance of hospitalization and 1-in-20 of death. Change the severity with lethality, it has changed budgets and interest. After all, there may be a Nobel prize for the team that 'cures the uncommon cold.'

Bob Wilson

 

1 in 5 chance of hospitalization based on limited testing numbers could change drastically with complete testing

 

Too late to edit. That should read 200 Million coronavirus common colds per year.

 

i think we're going to be dependent on medications and then hopefully some immunization. in the meantime, life on the inside will likely be topsy turvy

 

i don't buy the premise. i haven't read much about blaing animals. but i have read a lot about blaming humans.
not for the environment, but for eating bats

if anyone ever figures out where the virus came from, and how, that might help create a start to reducing the chances of another one.

 

Well, if you have a very low positive rate, the tests have sufficient sensitivity to allow them to pool samples by a factor or 10 or more. Then, if you get a hit, you go back and retest the individuals in the pool to see which one it was.

Here is Stanford's version:
Testing pooled samples for COVID-19 helps Stanford researchers track early viral spread in Bay Area | News Center | Stanford Medicine

So that reduces the problem to "only" 100,000 reactions per day

 

Provided there are enough supply of reagents to do PCR reactions, the bottle neck is not really the testing itself. Collecting 11 million samples is the rate limiting factor. Current PCR platform is highly scalable. A small lab with a right platform can handle 500-1000 reactions/day easily. If the money is no object, government owned (managed) labs can handle 1 million reactions/day.

 

business as usual around here. okay, so you can't get a haircut...

 

Dang! I'm already 3 months late since my last hair cut. If this keeps up, I'll be able to do a comb-over . . . not sure if it'll be head or eyebrows.

Bob Wilson

 

Large-scale simultaneous testing of 12,000 human-usable compounds against Sars Cov2. This non-peer-reviewed preprint has details but bottom line is that they found 7 compounds that had noticeable effectiveness at dose levels that would conceivably be safe for humans. (The oddest one was a proton-pump inhibitor.) Details:
A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals | bioRxiv

 

the conversation: 'human activities are responsible for viruses crossing over from bats and causing pandemics like coronavirus'

author: cellular microbiologist narveen jandu

 

hmm ~ I thought the general consensus from listening to all the science experts was that this virus wasn't possible to be a bat to human direct transfer thing going on. Is that now back in vogue?
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